Any body out there know about being on lupron depo injection to clear up endometreosis?
Answers:
If we were to believe the docs and Takeda Abbott Pharmaceutical's fancy marketing literature and website(s), we'd all think Lupron was the greatest thing since sliced bread. It's not.
First off, Lupron does not in any way "clear up" Endo. All it does is temporarily suppress the hormones, thereby - in theory - offering temporary relief of the disease. It does not offer relief in many who use it, and quelling of the hormones is not a cure for Endometriosis. Were that true, removal of the ovaries would be all that was needed and we know that's not the case. Secondly, it is *not indicated* for use in women who have had their uterus removed. That is an off-label usage for which there is no evidence supporting any supposed benefits. Thirdly, side effects of Lupron are potentially extremely negative and long-lasting, and include (as reported by the manufacturer itself) Asthenia, General pain, Headache, Hot flashes/sweats, Nausea/vomiting, GI disturbances, Edema, Weight gain/loss, Acne, Hirsutism, Joint disorder, Myalgia, Decreased libido, Depression/emotional lability, Dizziness, Nervousness, Neuromuscular disorders, Paresthesias, Skin reactions at injection site, Breast changes/tenderness/pain, Vaginitis, Flu-like symptoms, Heart palpitations, Syncope, Tachycardia, Appetite changes, Dry mouth, Thirst, Ecchymosis, Lymphadenopathy, Anxiety, Insomnia/Sleep disorders, Delusions, Memory disorder, Personality disorders, Rhinitis, Alopecia, Hair disorder, Nail disorder, Conjunctivitis, Ophthalmologic disorders, Taste perversion, and Dysuria.
And that's just a few. Check the prescribing literature or check a PDR for the long list.
Typically, users of Lupron experience what is known as Clinical Flare, which is an exacerbation of side effects and symptoms during the first 2 injections or so; after about the 3rd injection, the symptoms for which you are using the drug (i.e., Endometriosis) may begin to temporarily decrease.
Hopefully, you will be one of the lucky ones who only experiences minimal side effects for a short time and in whom the drug is effective and has no negative effects. Barring that, look into excision as the definitive treatment for Endo. It's not curative - there is no absolute cure - but excision can confer up 85% long term relief rates. There is a reason the true Endo experts don't use this drug and other GnRHs like it.
Good luck to you no matter what, you're not alone with this disease.
Other Answers:
My ex gf had that done, it brought relief, but it masculinized her a little. Once it wore off the endometriosis was back.
I am currently on Lupron 11.75 injection and my advice to you (and this is just from my personal experince) try to find alternative or do some MAJOR research..
I have stage 4 endo and continually get complex cysts on my one remaining ovary... Lupron is making me worse, imo..
Not only do the hot flashes and night sweats drive me up the wall and I sometimes wake up in the middle of the night soaked and sweating like I was Rocky..
And my sex drive, pfft, I have no sex drive, its completely gone..
And then there's the headaches, I've had a migraine for about 4 days now and it wont go away..
Not to mention my pain I had before has not gone away or gotten better...
And my moods have been crazy.. Im always freakin crying all the time, if I am not crying, Im depressed (and Ive never gotten sad or depressed in my life..)
And this is just within my first month..I am stuck with three injections since it was one three month injection..
Of course this is just my experience and every woman is different... You should just really really ask questions to your doctor about it and really do some research..
Some doctors just pawn it off like its a cure all but its no cure at all..
Good lucky sweetie with whatever you decide to do...
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