what is SLE. who can it affect.. What is the best cure for it.?




Answers:
Lupus (SLE) is an autoimmune disease that can affect virtually any system in the body. Think of it as a 'self-allergy' where the body attacks its own cells and tissues, causing inflammation, pain, and possible organ damage.

Many studies have shown that women are about 10 times more likely to have or to develop lupus than men. In Birmingham, the figures showed that lupus occurred in almost exactly one in 2,500 adult women; which shows that lupus is not a rare disease in women. It is however rare in men, occurring in approximately 1 in 25,000 adult men. Although the disease can start at any age, the first signs of the disease in women usually appear during the reproductive years (after the onset of menstrual periods and before the menopause). The disease is most commonly diagnosed in women between the ages of 20 and 40, and it appears to be milder in those in whom the disease starts after the menopause (when the monthly periods stop). There is no particular age pattern in men with lupus.

It is also well recognised that people from different ethnic and racial backgrounds are at different risks of developing lupus. People of West Indian origin are particularly likely to develop the disease, even when they are born and live in North America or the UK. Surprisingly, people of West African origin (from which the West Indian populations were descended) are at low risk of developing lupus. Studies have suggested that up to 1 in 250 women in Jamaica develop lupus. In Birmingham, 1 in 500 women of Afro-Caribbean background have lupus, compared with about 1 in 1000 women from India and Pakistan, and about 1 in 2,500 white European Caucasians. Other studies have shown that people of Chinese and Polynesian backgrounds are also at increased risk of developing lupus, compared with white Caucasians.


Although there is no cure for lupus, for the vast majority of people with the disease effective treatment can minimize symptoms, reduce inflammation, and maintain normal bodily functions. Medications often are prescribed for people with lupus, depending on which organ(s) are involved, and the severity of involvement. Commonly prescribed medications include:

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) – These drugs, such as aspirin and ibuprofen, are usually recommended for muscle and joint pain, and arthritis.

Acetaminophen – A mild analgesic used for pain, such as Tylenol.

Corticosteroids – Synthetically produced corticosteroids, such as Prednisone, are used to reduce inflammation and suppress activity of the immune system.

Antimalarials – These drugs, such as Plaquenil, are prescribed for skin and joint symptoms of lupus. It may take months before these drugs demonstrate a beneficial effect.

Immunomodulating Drugs – These drugs, such as Imuran and Cytoxan, act in a similar manner to the corticosteroid drugs in that they suppress inflammation and tend to suppress the immune system.

Biologic Drugs – These drugs include agents that block the production of specific antibodies, like those against DNA, or agents that act to suppress the manufacture of antibodies through other mechanisms.

Other Answers:
SLE stands for Systemic Lupus Erythmatosus and it affects mostly women of childbearing age. There is no cure, although there are a few treatments. Upon onset death usually occurs within 10 years.
It is Systemic lupus erythematosus.It is an autuimmune collagen disorder.Any person can be affected.There is no cure for it.One should take steroids,Immunosuppressants with Doctor's advice.



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